tPA_dosing_for_stroke_calculator v.1

The calculated dose of tPA used in patients with ischemic stroke.

Therese Lindberg

therese.lindberg@cambio.se

@CambioCDS

To calculate tPA dosing for stroke calculator.

Use to calculate tPA dosing for stroke calculator. Formula: 0.9 mg/kg IV, not to exceed 90 mg total dose. Administer 10% of the total dose as an initial IV bolus over 1 minute and the remainder infused over 60 minutes. Use in ischemic stroke patients only.

Not to be used in acute coronary syndrome or PE.

1. U.S. Food & Drug administration. Label for ACTIVASE. Acessdata FDA [Internet]. 2015 Feb [cited 2021 Feb 11]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/103172s5203lbl.pdf

openEHR-EHR-OBSERVATION.body_weight, openEHR-EHR-OBSERVATION.tpa_dosing