Migraine is an episodic disorder, most commonly consisting of severe headache, usually with photophobia (light sensitivity), phonophobia (sound sensitivity) and/or nausea (at times vomiting). It is one of the most frequent chief complaints presented to health care providers including neurologists and emergency medicine. Migraine typically affects more women than men, often peaking during 2 phases of life: puberty and/or perimenopause. Migraine can lead to significant amounts of mental, physical, financial, medical, societal and personal burden when not properly addressed. Migraine, as defined by the International Classification of Headache Disorders, third edition (ICHD-3), should include the following: 1. At least 5 or more attacks in lifetime 2. Headache attack lasting 4-72 hrs 3. At least 2 out of 4 features (unilateral location, pulsating/throbbing quality, moderate-severe intensity, aggravation by/causing avoidance of routine physical activity) 4. At least 1 of the following features (nausea and/or vomiting, photophobia and phonophobia)