chemo_radiat_score v.0

CHEMO-RADIAT Score is an evaluation model based on conventional cardiovascular risk factors, myocardial/ peripheral artery disease, obesity, renal failure, dyslipidemia, diabetes, and stroke/ ischemic attack associated with breast cancer treatment risk factors for predicting Major Cardiovascular Events (MACE).

Dimas Sumunar

dimas.sumunar@stud.ki.se

2022

The risk scoring system intended to estimate patient’s risk for major cardiovascular events after breast cancer treatment.

CHEMO-RADIAT model improves cardiovascular outcomes among patient diagnosed with breast cancer through the identification of cardiovascular events risk and support shared decision making for breast cancer therapeutic approach. CHEMO-RADIAT model consist of congestive heart failure, hypertension, elderly, myocardial infarction peripheral artery occlusive disease [PAOD], obesity, renal failure, abnormal lipid profile, DM, irradiation of the left breast, anthracycline dose, and transient ischemic attack/stroke. Patient with total score 0-2 considered low risk for MACE, while 3-5 is moderate risk and 6 or beyond is high risk.

The risk factors may have different cutoff point for different ethnic groups with high prevalence of smoking and obesity.

Kim, D. Y., Park, M. S., Youn, J. C., Lee, S., Choi, J. H., Jung, M. H., Kim, L. S., Kim, S. H., Han, S., & Ryu, K. H. (2021). Development and validation of a risk score model for predicting the cardiovascular outcomes after breast cancer therapy: The chemo-radiat score. Journal of the American Heart Association, 10(16). https://doi.org/10.1161/JAHA.121.021931

openEHR-EHR-OBSERVATION.atria_stroke_risk, openEHR-EHR-OBSERVATION.chadsvasc_score, openEHR-EHR-OBSERVATION.basic_demographic, openEHR-EHR-OBSERVATION.body_mass_index, openEHR-EHR-OBSERVATION.chemo_radiat_score, openEHR-EHR-EVALUATION.chemo_radiat_score, openEHR-EHR-OBSERVATION.estimated_glomerular_filtration_rate