Warfarin_Dosing_Calculator_guideline v.1
Warfarin Dosing Calculator determines the maintenance dose based on target INR, body surface area and bleeding risk factors.
To determine the maintenance dose based on target INR, body surface area and bleeding risk factors.
Formula: Warfarin dose in mg = exp [0.613 + (0.425 x BSA in m2) - (0.0075 x Age) + (0.156 x African-American race) + (0.216 x Target INR) - (0.257 x Amiodarone) + (0.108 x Smoker) + (0.0784 x DVT/PE)] Where: BSA in m2 = (Weight in kg)0.425 x (Height in cm)0.725 x 0.007184
Gage BF, Eby C, Johnson JA, Deych E, Rieder MJ, Ridker PM, Milligan PE, Grice G, Lenzini P, Rettie AE, Aquilante CL, Grosso L, Marsh S, Langaee T, Farnett LE, Voora D, Veenstra DL, Glynn RJ, Barrett A, McLeod HL. Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther. 2008 Sep;84(3):326-31. doi: 10.1038/clpt.2008.10. Epub 2008 Feb 27. Erratum in: Clin Pharmacol Ther. 2008 Sep;84(3):430. PMID: 18305455; PMCID: PMC2683977.
openEHR-EHR-OBSERVATION.basic_demographic, openEHR-EHR-OBSERVATION.body_weight, openEHR-EHR-OBSERVATION.body_surface_area, openEHR-EHR-OBSERVATION.height, openEHR-EHR-OBSERVATION.warfarin_dosing_calculator
