Sokal Index for Chronic Myelogenous Leukemia (CML) predicts survival of CML based on clinical and lab information.
To calculate the total sum for Sokal index.
Use to predict the survival of CML. The Sokal index is calculated by using the following formula: Sokal Score = exp([0.0116 × (age in years – 43.4)] + [0.0345 × (spleen size in cm – 7.51)] + [0.188 x ((platelets in 109/L / 700)2 – 0.563)] + [0.0887 × (blasts in % – 2.10)]) Interpretation: Risk Group Sokal Score 2-year Survival Median Survival Low <0.8 90% 5 years Intermediate 0.8–1.2 65-90% 2.5-5 years High >1.2 65% 2.5 years
Sokal JE, Cox EB, Baccarani M, Tura S, Gomez GA, Robertson JE, Tso CY, Braun TJ, Clarkson BD, Cervantes F, et al. Prognostic discrimination in "good-risk" chronic granulocytic leukemia. Blood. 1984 Apr;63(4):789-99. PMID: 6584184.
openEHR-EHR-OBSERVATION.sokal, openEHR-EHR-OBSERVATION.lab_test-full_blood_count, openEHR-EHR-EVALUATION.sokal_assesment, openEHR-EHR-OBSERVATION.basic_demographic