Albumin_Globulin_Ratio_guideline v.1

Determines how the amount of albumin in blood compares with the other protein in the blood, globulins.

Maryam Razavi

maryam.razavi@cambio.se

© Cambio CDS

To determine how the amount of albumin in blood compares with the other protein in the blood, globulins.

Formula: A/G Ratio = Albumin in g/dL / (Total Protein in g/dL – Albumin in g/dL) Interpretation A/G ratios of less than 1 are clinically significant, indicating that globulin proteins exceed the albumin protein.

Busher JT. Serum Albumin and Globulin. In: Walker HK, Hall WD, Hurst JW, editors. Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition. Boston: Butterworths; 1990. Chapter 101. Available from: https://www.ncbi.nlm.nih.gov/books/NBK204/ Lv GY, An L, Sun XD, Hu YL, Sun DW. Pretreatment albumin to globulin ratio can serve as a prognostic marker in human cancers: a meta-analysis. Clin Chim Acta. 2018 Jan;476:81-91. doi: 10.1016/j.cca.2017.11.019. Epub 2017 Nov 21. PMID: 29170102. Duran AO, Inanc M, Karaca H, Dogan I, Berk V, Bozkurt O, Ozaslan E, Ucar M, Eroglu C, Ozkan M. Albumin-globulin ratio for prediction of long-term mortality in lung adenocarcinoma patients. Asian Pac J Cancer Prev. 2014;15(15):6449-53. doi: 10.7314/apjcp.2014.15.15.6449. PMID: 25124641.

openEHR-EHR-OBSERVATION.lab_test-liver_function, openEHR-EHR-OBSERVATION.albumin_globulin_ratio, openEHR-EHR-EVALUATION.albumin_globulin_ratio